Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity linked to bortezomib, a proteasome inhibitor used in the therapy of multiple myeloma. Its synthesis or analyze is very important for guaranteeing the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets specific sorts of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the generation process and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to treat breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the remedy of breast most cancers. Many intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy GeMcitabine Intermediate 8 drug helpful in treating cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the remedy of colorectal most cancers and compact cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated Canagliflozin Intermediate2 with the synthesis of varied gluconic acid derivatives, which might be Employed in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication used to handle sort 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).